对正常淋巴细胞和恶变淋巴细胞做表型分析不仅采用细胞内酶测定法,而且用高度特异抗血清和特有的表面标志测定。这不仅可知白血病的来源,而且可了解到淋巴细胞分化的程度。但在发现单克隆抗体以前,应用异种抗血清或人自身免疫血清只能鉴定有限的T细胞亚群,而用单克隆抗体能够鉴定一系列T淋巴细胞抗原。淋巴细胞上分子量 Phenotypic analysis of normal lymphocytes and malignant lymphocytes was performed using not only intracellular enzyme assays but also highly specific antisera and specific surface markers. This not only shows the source of leukemia, but also understand the extent of lymphocyte differentiation. However, prior to the discovery of monoclonal antibodies, the use of either heterologous antisera or human autoimmune sera can only identify a limited subset of T cells, whereas monoclonal antibodies can identify a range of T lymphocyte antigens. Lymphocyte molecular weight