论文部分内容阅读
目的 探讨晚发性维生素K缺乏症 (简称晚K缺乏症 )并颅内出血患儿血清镁离子 (Mg2 + )水平与临床的关系。方法 对 6 8例确诊晚K缺乏症并颅内出血患儿 (出血组 )于入院当天及 30例儿保科正常体检的婴儿(正常对照组 )采取静脉血测定血清Mg2 + 水平。结果 颅内出血患儿Glasgows评分 >7分、5～ 7分、≤ 4分组血清Mg2 + 分别为 (0 80± 0 0 6 )、(0 6 4± 0 10 )、(0 5 6± 0 0 8)mmol/L ,均低于正常对照组 (0 84± 0 0 5 )mmol/L。>7分组与对照组比较差异无显著性 (P >0 0 5 ) ,5～ 7分组与对照组及 >7分组比较差异有显著性 (P <0 0 5 ) ,≤ 4分组与对照组及 >7分组比较差异有非常显著意义 (P <0 0 1)。Glasgows评分越低 ,血清Mg2 + 下降越明显。单纯出血组血清Mg2 + (0 79± 0 0 7)mmol/L与合并有脑梗死、缺氧缺血性病变组 (0 6± 0 14 )mmol/L比较差异有显著性 (P <0 0 5 ) ,与对照组比较差异无显著性 (P >0 0 5 )。结论 颅内出血病情越重血清Mg2 + 水平下降越显著 ,血清Mg2 + 测定对病情判断及治疗有指导意义。
Objective To investigate the relationship between serum magnesium (Mg 2+) and clinical manifestations in children with late onset vitamin K deficiency (K deficiency) and intracranial hemorrhage. Methods Serum levels of Mg2 + were measured in 68 infants with delayed K deficiency and intracranial hemorrhage (hemorrhage group) and 30 infants (normal control group) on the day of admission and normal control group. Results The Glasgows score of patients with intracranial hemorrhage was> 7, 5 ~ 7, ≤ 4, respectively, ) mmol / L, all lower than the control group (0 84 ± 0 0 5) mmol / L. (P> 0.05). There was a significant difference between the 5 ~ 7 group and the control group and the> 7 group (P <0 05), and the difference between the 4 group and the control group was not significant > 7 group differences were significant (P <0 01). The lower the Glasgows score, the more obvious the decrease of serum Mg2 +. The level of serum Mg2 + (0 79 ± 0 0 7) mmol / L in pure hemorrhage group was significantly higher than that in cerebral infarction group and 0 6 ± 0 14 mmol / L hypoxic-ischemic group (P <0 0 5), no significant difference compared with the control group (P> 0.05). Conclusions The more severe the intracranial hemorrhage, the more the serum Mg2 + level declines obviously. The determination of serum Mg2 + has a guiding significance in judging and treating the disease.