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目的:评价经尿道绿激光联合盐酸吡柔比星(THP)术前膀胱灌注对非肌层浸润性膀胱癌的疗效。方法:选取50例非肌层浸润性膀胱癌患者,随机分为绿激光联合术前THP膀胱灌注组28例与单纯绿激光组22例。对两组病变检出率,术后复发率等指标进行比较。结果:两组病例均一次手术成功。绿激光联合术前THP膀胱灌注组对病变检出率、术后复发率与单存绿激光组进行比较,差异有统计学意义(P<0.05)。结论:绿激光联合术前膀胱灌注盐酸吡柔比星(THP)可提高非肌层浸润性膀胱癌病变检出减少、漏诊漏治,降低术后复发率。
Objective: To evaluate the efficacy of transurethral green laser combined with pirarubicin hydrochloride intravesical instillation on non-muscle invasive bladder cancer. Methods: Fifty patients with non-myasthenic invasive bladder cancer were randomly divided into two groups: green laser combined with preoperative THP intravesical instillation group (n = 28) and pure green laser group (n = 22). The detection rate of two groups of lesions, postoperative recurrence rate and other indicators were compared. Results: Two surgeries were successful in one operation. The detection rate of the lesion, postoperative recurrence rate and single green laser group were significantly different between the green laser group and the preoperative THP group (P <0.05). CONCLUSION: Green laser combined with preoperative intravesical instillation of pirarubicin hydrochloride (THP) can reduce the number of non-muscle invasive bladder cancer detection, missed diagnosis and treatment, and reduce the recurrence rate.