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在HBV感染者的血清中存在着两种形式的抗-HBc IgM抗体(IgM抗-HBc),急性患者主要为19S五聚体IgM抗-HBc,而慢性患者则以7-8S单体IgM抗-HBc更多见。为确定急慢性HDV感染患者IgM抗-HD的存在情况,了解19S或7-8SIgM抗-HD出现频率及其临床意义,作者采用新近发展的用于确定IgM抗-HD的特异性免疫检测方法,对24例急慢性HD进行了检测。其中9例为急性患者,15例为慢性患者。急性患者中5例为重叠感染,4例为HDV和HBV联合感染。肝活检证实15例慢
There are two forms of anti-HBc IgM antibodies (IgM anti-HBc) in the serum of HBV-infected individuals, the 19S pentamer IgM anti-HBc in acute patients and the 7-8S monomeric IgM anti-HBs -HBc See more. To determine the presence of IgM anti-HD in patients with acute and chronic HDV infection and to understand the frequency of anti-HD 19S or 7-8SIgM and its clinical significance, the authors used a newly developed specific immunoassay for the determination of anti-HD IgM, 24 cases of acute and chronic HD were tested. Nine of them were acute and 15 were chronic. Five of the acute patients had overlapping infections, and four had combined HDV and HBV infection. Liver biopsy confirmed 15 cases of slow