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目的探讨硝苯地平缓释片联合厄贝沙坦治疗2型糖尿病肾病的临床疗效。方法分析郑州公交医院收治的156例2型糖尿病肾病患者的临床资料,156例随机分为对照组和观察组,两组在常规治疗基础上,对照组给予硝苯地平缓释片,观察组给予硝苯地平缓释片联合厄贝沙坦,观察两组治疗后血压、血脂及24 h尿微量白蛋白排泄率变化。结果观察组血压、血脂及24 h尿微量白蛋白排泄率均低于对照组,两组比较差异有统计学意义(P<0.05)。结论硝苯地平缓释片联合厄贝沙坦治疗2型糖尿病肾病疗效显著。
Objective To investigate the clinical efficacy of nifedipine sustained-release tablets combined with irbesartan in the treatment of type 2 diabetic nephropathy. Methods The clinical data of 156 patients with type 2 diabetic nephropathy admitted in Zhengzhou Public Transport Hospital were analyzed. 156 patients were randomly divided into control group and observation group. On the basis of routine treatment, the control group was given nifedipine sustained-release tablets and the observation group was given Nifedipine sustained-release tablets combined with irbesartan, blood pressure, blood lipid and 24 h urinary albumin excretion rate were observed after treatment. Results The blood pressure, blood lipids and 24 h urinary albumin excretion rate in the observation group were lower than those in the control group. There was significant difference between the two groups (P <0.05). Conclusion Nifedipine sustained-release tablets combined with irbesartan treatment of type 2 diabetic nephropathy significant effect.