目的对浙南沿海地区鼠形动物及鼠疫、肾综合征出血热(HFRS)及钩端螺旋体病(简称钩体病)等鼠传疾病流行情况进行监测,探索鼠传疾病综合监测模式,为制定该地区鼠传疾病防控策略提供科学依据。方法在浙南沿海地区选择龙湾区、文成县和洞头县为监测点,分别开展宿主动物、病原学和血清学监测。结果 2013-2014年温州市共报告HFRS病例32例,发病率为0.17/10万;报告钩体病2例,发病率为0.01/10万。各鼠疫监测点共捕获各种宿主动物2目2科5属10种共1 652只,主要鼠形动物为臭和褐家鼠,分别占44.53%和22.99%;发现染蚤鼠77只,染蚤率为3.14%;捕蚤273匹,总蚤指数为0.11,缓慢细蚤为优势寄生蚤,占77.29%。未检出鼠疫耶尔森菌、伯氏疏螺旋体和肾综合征出血热病毒阳性标本;PCR检测发现多种鼠形动物感染巴贝西虫、巴尔通体、立克次体、莱姆钩端螺旋体、无形体和查菲埃立克体等病原体。结论浙南沿海地区鼠疫宿主和媒介分布广泛,种群较多,沿海、山区和平原宿主动物分布不一,应加强鼠传疾病宿主和媒介监测以及病原学监测,整合鼠传疾病单项监测和鼠类病媒生物监测,减少人力物力浪费。开展鼠传疾病危害风险评估,积极防范鼠传疾病暴发流行,防止鼠疫输入性病例引起当地暴发流行。 Objective To monitor the prevalence of rodent diseases such as murine and plague plague, hemorrhagic fever with renal syndrome (HFRS) and leptospirosis (leptospirosis) in the coastal areas of southern Zhejiang Province, and to explore the comprehensive monitoring mode of rodent disease, Rodent disease prevention and control strategies in this area provide a scientific basis. Methods Longwan, Wencheng and Dongtou counties were selected as the monitoring points in the coastal areas of southern Zhejiang to carry out host animal, etiological and serological surveillance respectively. Results A total of 32 cases of HFRS were reported in Wenzhou from 2013 to 2014, with an incidence of 0.17 / 100 000. Two cases of leptospirosis were reported, with a prevalence of 0.01 / 100 000. A total of 1 652 species of 2 species, 5 genera, 2 families, 2 families, 2 families and 2 rodents were captured in each plague surveillance spot. The main rodent animals were stinky and brown locusts, accounting for 44.53% and 22.99% respectively. 77 stained fleas were found, Flea rate was 3.14%; flea flea 273, total flea index was 0.11, slow flea flea is dominant, accounting for 77.29%. No positive strains of Yersinia pestis, Borrelia burgdorferi, and Hemorrhagic fever with renal syndrome were detected. PCR detection revealed that a large number of mouse-type animals were infected with Babesia, Bartonella, Rickettsia, , Anaplasma and Chafi Ehrlichia and other pathogens. Conclusion Host and vector of plague are widely distributed in the coastal areas of south Zhejiang. There are many populations and host animals in coastal area, mountainous area and plains are distributed differently. Host and vector surveillance and etiological monitoring should be strengthened. Vector bio-monitoring to reduce waste of manpower and material resources. To carry out risk assessment of mouse-borne diseases, and actively prevent outbreaks of rodent diseases to prevent imported cases of plague caused by local outbreaks.