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地中海贫血初见于地中海各民族,一九二五年 Cooly 等确定此病,并以地中海命名。后在其他地区也有报告。国内于一九四○年——一九五四年间先后在广州地区发现该病,继一九五八年张肖白报告
Mediterranean anemia was first seen in all ethnic groups in the Mediterranean. In 1925 Cooly et al identified the disease and named it the Mediterranean Sea. Later in other areas there are reports. The disease was found in Guangzhou in 1940-1954 successively. Following the report of Zhang Xiao Bai in 1958