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在383名 AMI 病人中施行了 PTCA。溶栓组282例,非溶栓组101例(心源性休克,年龄≥75岁,做过冠状动脉旁路手术者,AMI 发生时间>6小时)。结果:溶栓治疗与未溶栓治疗两组有相似的再灌注成功率(92%、88%),不致命的再梗塞率(6.0%、5.9%)和复发的心肌缺血率(1.8%、0%);死亡率溶栓组为低(3.9%∶24%,P<0.0001),出血发生率亦较低(4.6%∶10.9%,P<0.05)。血管造影说明左室射血历能提高率为4.4%,而未溶栓组为10.5%(P<0.002),前壁AMI 病人左室射血功能有很大提高(溶栓组7.7%,未溶栓组15.1%).再灌注时间>6小时的病人左室射血功能亦有很大提高(14.2%).
PTCA was administered to 383 AMI patients. Thrombolytic group of 282 cases, 101 cases of non-thrombolytic group (cardiogenic shock, age ≥ 75 years, done coronary artery bypass surgery, AMI occurred more than 6 hours). Results: The success rate of reperfusion (92%, 88%), non-fatal re-infarct rate (6.0%, 5.9%) and recurrent myocardial ischemia rate (1.8% , 0%). The death rate was lower in the thrombolytic group (3.9% vs. 24%, P <0.0001). The bleeding rate was also lower (4.6% vs10.9%, P <0.05). Angiography showed a 4.4% improvement in LVEF, compared with 10.5% for those without thrombolysis (P <0.002), and a significant improvement in left ventricular ejection function in patients with anterior AMI (7.7% for thrombolysis Thrombolysis group 15.1%). Patients with reperfusion time> 6 hours also had a significant improvement in left ventricular ejection function (14.2%).