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目的:评价人工流产术前、术后应用缩宫素鼻喷雾剂对减少术中和术后出血的临床效果。方法:试验组200例在手术开始前给予缩宫素鼻喷雾剂,左、右侧鼻腔各1喷(共8 U),术后每日4次直至阴道出血结束。对照组200例不使用缩宫素鼻喷雾剂。观察患者术中出血量、手术时间和术后阴道出血天数。结果:术中出血量试验组为5.6±2.2 ml,对照组为10.9±8.1 ml(t=8.87,P<0.01);手术时间试验组为7.2±2.0 min,对照组为7.6±1.8 min(t=1.264,P>0.05);术后平均阴道出血天数试验组为5.0±1.9 d,对照组为6.2±1.7 d(t=6.474,P<0.01)。结论:人工流产术前、后给予缩宫素鼻喷雾剂能显著减少手术中和手术后出血。
Objective: To evaluate the clinical effect of using oxytocin nasal spray before and after induced abortion to reduce intraoperative and postoperative bleeding. Methods: 200 cases in trial group were given oxytocin nasal spray before operation, 1 spray (8 U) in left and right nasal cavity, and 4 times daily until the end of vaginal bleeding. The control group of 200 patients did not use oxytocin nasal spray. Observe the amount of intraoperative blood loss, operation time and postoperative vaginal bleeding days. Results: The intraoperative blood loss was 5.6 ± 2.2 ml in the test group and 10.9 ± 8.1 ml in the control group (t = 8.87, P <0.01). The operation time was 7.2 ± 2.0 min in the test group and 7.6 ± 1.8 min in the control group (t = 1.264, P> 0.05). The mean postoperative vaginal bleeding days was 5.0 ± 1.9 days in the test group and 6.2 ± 1.7 days in the control group (t = 6.474, P <0.01). Conclusions: Oxytocin nasal spray before and after induced abortion can significantly reduce intraoperative and postoperative bleeding.