中枢性睡眠呼吸暂停正常成年人在快速睡眠时或在高原,可发生中枢性睡眠呼吸暂停。老年人或婴儿睡眠时的周期性低通气也与中枢因素有关。病理性中枢性睡眠呼吸暂停可见于多种疾患:■神经系统病变如脊髓前侧切断术、血管栓塞或变性病变引起的双侧后侧脊髓病变;■自主神经功能异常,如家族性自主神经异常,胰岛素相关的糖尿病,shy-Drager综合征、脑炎、脑干肿瘤; Central sleep apnea Normal adults may develop central sleep apnea during fast sleep or at high altitude. Periodic hypoventilation in the elderly or infants is also related to central factors. Pathologic central sleep apnea can be seen in a number of conditions: ■ Nervous system disorders such as bilateral posterior spinal cord lesions caused by anterior spinal cord transection, vascular embolism, or degenerative lesions; ■ Autonomic dysfunction such as familial autonomic dysfunction , Insulin-related diabetes, shy-Drager syndrome, encephalitis, brain stem tumors;