口腔癌是头颈部常见的恶性肿瘤 ,病理分级多属中、高分化癌 ,区域性淋巴转移率高 ,而全身远位转移率较低 ,对放、化疗敏感性差 ,原发灶的失控是导致患者死亡的主要原因 ,各期平均 5年生存率在5 0 %～ 60 %之间[1,2 ] ,故探讨有效的治疗方法是临床面临的重大课题。近年来恶性肿 Oral cancer is a common malignant tumor of the head and neck. Most of the pathological grading is medium and well differentiated carcinoma. The regional lymphatic metastasis rate is high while the distant metastasis rate of the whole body is low. The sensitivity to radiotherapy and chemotherapy is poor. Leading to death of patients the main reason, the average 5-year survival rate of each period of 50% to 60% [1,2], so to explore effective treatment is a major clinical issue. In recent years, malignant swelling