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很多血液病与骨髓造血功能的改变有关。骨髓穿刺是检查多数血液病患者不可缺少的一个方法,通常将骨髓液制成涂片观察,只能观察造血细胞的多少,各种造血细胞间的比例关系及造血细胞本身有否病变,而不能观察骨髓的构造。Trentin(1970)提出造血微环境的概念,认为一个多能造血干细胞之所以分化成为粒细胞、红细胞或巨核细
A lot of blood diseases and changes in bone marrow function. Bone marrow biopsy is an indispensable method to check the majority of patients with hematological diseases, bone marrow fluid is usually smear observation, only the number of hematopoietic cells observed, the ratio between the various hematopoietic cells and hematopoietic cells have their own lesions, not Observe bone marrow structure. Trentin (1970) proposed the concept of hematopoietic microenvironment, that a pluripotent hematopoietic stem cell differentiated into granulocytes, erythrocytes or megakaryocytes