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有设想早老性痴呆症即是由于脑内慢性炎症而引发。关节炎也是慢性炎症,可用非甾体抗炎药治疗,早老性痴呆是否也同样可用非甾体抗炎药治疗。1993年4月在美国费城举行的一次学术报告会上,有报告以吲哚美辛(indomethacin)对老年性痴呆症进行双盲临床试验。44名患者半数服用吲哚美辛,半数给予安慰剂,疗程6个月。结果给药组患者病症进程明显减慢。认别试验指标在服药期间记忆力保持稳定,未再退化。过去日本医师用氨苯砜(dapsone)治疗4000例麻风病患者的5年
It is assumed that Alzheimer’s disease is triggered by chronic inflammation in the brain. Arthritis is also a chronic inflammation that can be treated with NSAIDs and whether Alzheimer’s disease is also treated with NSAIDs. At a symposium held in Philadelphia, USA, in April 1993, a double-blind clinical trial of indomethacin on Alzheimer’s disease was reported. Half of 44 patients took indometacin, and half of them were given placebo for 6 months. Results The course of the disease in the administration group was significantly slowed down. Identify test indicators during the medication memory remained stable, no further degradation. In the past, Japanese physicians treated 4,000 leprosy patients for 5 years with dapsone