论文部分内容阅读
慢性粒细胞性白血病(CGL)是1845年由Graigie等首先发现。本病的治疗大概经历下述三个阶段:Lissauer于1865年首次用砷剂治疗本病;Pusey于1902年用X线照射脾区取代砷剂治剂;Haddow等于1953年介绍应用马利兰,成为治疗CGL的标准疗法。此后,CGL的治疗未能取得突破性的进展。然而,有关CGL的基础知识研究进展较快,治疗上也积累了宝贵的经验,为最后攻克CGL提供了有用的资料。现摘要概述如下。
Chronic myeloid leukemia (CGL) was first discovered by Graigie et al in 1845. The treatment of this disease probably goes through three phases: Lissauer first treated the disease with arsenic in 1865; Pusey replaced the arsenic agent with a radiographic spleen in 1902; Haddow was introduced in 1953 as a treatment CGL’s standard therapy. Since then, CGL treatment failed to make a breakthrough. However, the research on the basic knowledge of CGL is progressing rapidly, and valuable experience has been accumulated in the treatment, which provides useful information for the final resolution of CGL. The summary is summarized below.