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目的:通过对血清同型半胱氨酸(Homocysteine,HCY)和超敏C反应蛋白(Hs-CRP)联合检测,了解其与急性冠脉综合征(ASC)的关联,并着重于ACS各型分析,以期能通过检测分析,了解ASC各型HCY、Hs-CRP的变化情况,为ASC的早期诊断、分型、治疗、预后判断提供依据。方法:分别采用循环酶法和透射比浊法检测正常对照组与冠心病组患者血清中HCY和Hs-CRP水平,进行统计分析。结果:经分析,ASC组HCY、Hs-CRP水平与正常对照组有显著差异(P<0.01,有统计意义)。结论:高HCY血症是冠心病的独立危险因素[1],Hs-CRP与冠心病的发生、发展有显著正相关性,此二项目联合检测更有助于疾病的诊断与分型,建议将这两个指标作为冠心病的常规检测项目。
OBJECTIVE: To investigate the association between serum homocysteine (HCY) and hypersensitive C-reactive protein (Hs-CRP) in patients with acute coronary syndrome (ACS) , In order to detect ASC analysis of HCY, Hs-CRP changes, ASC diagnosis, classification, treatment, prognosis provide the basis. Methods: The levels of HCY and Hs-CRP in the serum of patients with coronary heart disease and control group were detected by cyclic enzyme and turbidimetry, respectively. Statistical analysis was performed. Results: After analysis, HCY and Hs-CRP levels in ASC group were significantly different from those in normal control group (P <0.01, statistically significant). CONCLUSIONS: Hyperhomocysteinemia is an independent risk factor for CHD [1]. There is a significant positive correlation between Hs-CRP and the occurrence and development of coronary heart disease. The combined detection of these two items is more helpful for the diagnosis and classification of the disease. These two indicators as a routine test of coronary heart disease.