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目的探讨系统性淋巴结清扫术联合化疗用于非小细胞肺癌治疗对患者疗效及预后的影响。方法将非小细胞肺癌患者206例随机分为研究组和对照组各103例,研究组采用系统性淋巴结清扫术治疗,对照组采用单纯肺门淋巴结清扫术治疗,2组患者均联合化疗进行治疗,比较2组患者每例患者淋巴结清扫个数和每例患者淋巴结清扫组数,观察2组患者的中位生存期和1年生存率。结果研究组每例患者淋巴结清扫个数和每例患者淋巴结清扫组数均显著多于对照组,中位生存期长于对照组,1年生存率高于对照组,差异均有统计学意义(P<0.05)。结论系统性淋巴结清扫术联合化疗用于非小细胞肺癌治疗能有效提高患者疗效,改善预后情况,适合在临床中广泛推广应用。
Objective To investigate the effect of systemic lymphadenectomy combined with chemotherapy on the efficacy and prognosis of patients with non-small cell lung cancer. Methods 206 patients with non-small cell lung cancer were randomly divided into study group and control group, 103 cases in each group. The study group was treated with systemic lymph node dissection and the control group with simple hilar lymph node dissection. Both groups were treated with chemotherapy The number of lymph nodes dissection and the number of lymph node dissection per patient in each group were compared. The median survival time and 1-year survival rate were compared between the two groups. Results The number of lymph node dissection and lymph node dissection per patient in study group was significantly higher than that in control group, and the median survival time was longer than that in control group. The 1-year survival rate was significantly higher than that in control group (P <0.05). Conclusion The combination of systemic lymphadenectomy and chemotherapy for the treatment of non-small cell lung cancer can effectively improve the curative effect and prognosis of the patients, and is suitable for wide application in clinic.