目的探讨鼻唇沟岛状皮瓣修复口底组织缺损的疗效。方法 2010年7月-2013年7月,采用以面动脉下端为蒂的鼻唇沟岛状皮瓣修复口底组织缺损13例。男7例,女6例;年龄36~73岁,平均58岁。缺损均为病变切除所致,其中白斑4例,红斑2例,舌下腺黏液表皮样癌1例,口底癌2例,舌癌4例。单纯口底缺损5例;合并舌体缺损6例,牙龈缺损2例。其中6例仅累及黏膜及黏膜下层,7例累及舌下腺及舌肌或牙槽突。口底组织缺损直径1~4 cm,皮瓣切取范围为4.5 cm×2.0 cm~6.5 cm×3.5 cm。结果患者均顺利完成手术,皮瓣均成活,供、受区创面均Ⅰ期愈合。13例均获随访,随访时间5~24个月,平均11个月。未见肿瘤复发;患者进食、吞咽、语言等功能接近正常。供区无明显畸形。结论鼻唇沟岛状皮瓣移位灵活、操作简便、成活率高、供区损伤小,适宜于口底轻中度缺损修复。 Objective To investigate the efficacy of nasolabial island skin flap in repairing mouth defects. Methods From July 2010 to July 2013, 13 cases of oral mucosal defects were repaired with the island flap of the nasolabial fold pedicled with the lower facial artery. 7 males and 6 females; aged 36 to 73 years, mean 58 years. The lesions were all caused by excision of the lesion. There were 4 cases of leukoplakia, 2 cases of erythema, 1 case of sublingual gland mucoepidermoid carcinoma, 2 cases of oral floor carcinoma and 4 cases of tongue carcinoma. Simple mouth defects in 5 cases; combined defect in 6 cases, 2 cases of gum defects. Six of them only involved mucosa and submucosa, and seven involved sublingual glands and lingual muscles or alveolar processes. The diameter of the defect in the floor of the mouth was 1 ~ 4 cm in diameter, and the range of flap flap was 4.5 cm × 2.0 cm ~ 6.5 cm × 3.5 cm. Results All patients successfully completed the operation and the flaps survived. All the wounds were healed by first intention. Thirteen patients were followed up for 5-24 months with an average of 11 months. No tumor recurrence; patients eating, swallowing, language and other functions close to normal. No significant deformity for the area. Conclusion The nasolabial fold island flap is flexible and easy to operate with high survival rate and less damage to the donor site, which is suitable for the repair of mild and moderate floor defects.