【摘 要】
:
DNA 探针重组技术已用于证实与冠状动脉硬化有关的载脂蛋白 AⅠ-CⅢ-AⅣ基因位点的 DNA变异,为该病提供潜在的基因标记。非胰岛素依赖型糖尿病(NIDDM)与同龄非糖尿病相比,冠
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DNA 探针重组技术已用于证实与冠状动脉硬化有关的载脂蛋白 AⅠ-CⅢ-AⅣ基因位点的 DNA变异,为该病提供潜在的基因标记。非胰岛素依赖型糖尿病(NIDDM)与同龄非糖尿病相比,冠心病发病率约高2倍。过去虽然对糖尿病引起动脉硬化的各种环境因素进行过深入研究,但忽略了遗传因素的作用。为此,作者在一组伴有冠心病的 NIDDM患者对其载脂蛋白 CⅢ(apo-CⅢ)的基因型分布进行
DNA probe recombination technology has been used to confirm DNA variants of the apolipoprotein AI-CIII-AIV gene locus associated with coronary arteriosclerosis, providing a potential genetic marker for the disease. Non-insulin-dependent diabetes mellitus (NIDDM) compared with the same age non-diabetic, coronary heart disease incidence of about 2 times higher. In the past, although various environmental factors of atherosclerosis caused by diabetes were studied in depth, the role of genetic factors was neglected. To this end, the author in a group of patients with NIDDM coronary heart disease its apolipoprotein C Ⅲ (apo-C Ⅲ) genotype distribution
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