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采用改良的Ｈｅｎｓｏｎ法检测了１６例原发性肾病综合征（ＰＮＳ）患者血浆血小板激活因子（ＰＡＦ）含量，结果显示：ＰＮＳ患者血浆ＰＡＦ含量较正常对照组显著升高（Ｐ＜０．００１）。血浆ＰＡＦ含量与尿蛋白排泄量呈正相关（γ＝０．７７，Ｐ＜０．０１），提示ＰＡＦ可能参于ＰＮＳ的发病，ＰＡＦ是诱导肾小球基底膜对蛋白质通透性增加的一个重要介质。
A modified Henson method was used to detect the platelet-activating factor (PAF) in 16 patients with primary nephrotic syndrome (PNS). The results showed that plasma PAF levels in PNS patients were significantly higher than those in normal controls (P <0.001) . Plasma PAF content and urinary protein excretion was positively correlated (γ = 0.77, P <0.01), suggesting that PAF may be involved in the pathogenesis of PNS, PAF is induced glomerular basement membrane permeability of protein is an important medium.