目的 :肺动脉平滑肌细胞钾离子通道活性与缺氧性肺动脉高压关系是近年研究热点 ,改变这些钾离子通道活性能直接影响血管张力。缺氧可阻断延迟整流性钾通道或 /和钙离子激活性钾通道 ,引起肺动脉平滑肌细胞收缩 ,使肺动脉压升高。目前 ,国内有关肺动脉平滑肌细胞钾离子通道活性 PURPOSE: The relationship between potassium channel activity of pulmonary artery smooth muscle cells and hypoxic pulmonary hypertension is a hot topic in recent years. Altering the activity of these potassium channels can directly affect the vascular tone. Hypoxia can block the delayed rectifier potassium channels and / or calcium-activated potassium channels, causing pulmonary artery smooth muscle cell contraction, pulmonary hypertension. At present, the domestic potassium channel activity of pulmonary artery smooth muscle cells