侵袭转移是恶性肿瘤的生物学特征之一,在恶性肿瘤的发生、发展中发挥重要作用。肿瘤的浸润、转移是一个相当复杂的多步骤过程,主要包括细胞黏附、基质分解及远处转移3个环节。小细胞肺癌约占肺癌的20%,其侵袭力强,极易发生早期转移。现就小细胞肺癌侵袭转移相关蛋白的研究近况,为小细胞肺癌的诊断和治疗提供有效的途径。 Invasion and metastasis is one of the biological characteristics of malignant tumors, and plays an important role in the occurrence and development of malignant tumors. Tumor invasion, metastasis is a very complex multi-step process, including cell adhesion, stromal decomposition and distant metastasis 3 links. Small cell lung cancer accounts for about 20% of lung cancer, its strong invasion, prone to early metastasis. Now on the invasion and metastasis of small cell lung cancer-related protein status, for the diagnosis and treatment of small cell lung cancer provide an effective way.