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作者对400例中期妊娠采用前列腺素 E_2(PGE_220mg 阴道内反复给药进行引产,对其安全性及效果进行评价。受试者分为3个治疗组:甲组232例单用 PGE_2,每3小时在阴道后穹窿放入 PGE_220mg 直至流产,未用附加治疗;乙组106例,在使用 PGE_2首次剂量前先在宫颈管安放一个中号昆布塞条;丙组62例除在宫颈管安放昆布塞条外,同时在安放2小时后静滴催产素(滴速为每分钟139mu),持续滴到完全流产后为止。由于不同治疗结果无显著差异,最后采取在妊娠16～19周的受试者,单用 PGE_2。全组受试者治疗前均用复方苯乙哌啶及安定。完全流产成功率82％
The author of 400 cases of pregnancy with prostaglandin E_2 (PGE_220mg intravaginally repeated induction of induction of labor, the safety and efficacy were evaluated subjects were divided into three treatment groups: Group A 232 cases of PGE 2, every 3 hours In the vaginal posterior fornix into PGE_220mg until abortion, without additional treatment; Group B 106 patients before the first dose of PGE_2 in the cervical canal placed a medium kelp plug; C group 62 in addition to the cervical canal to place kelp plug , While intravenous infusion of oxytocin 2 hours after placement (drip rate of 139mu per minute), continued dropping until complete abortion so far .Because the results of different treatments no significant difference, the last to take 16 to 19 weeks of pregnancy in subjects, Single PGE_2 .Three groups of subjects before treatment with compound diphenoxylate and diazepam.The success rate of complete abortion was 82%