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目的评价临床药师对指导骨科临床抗菌药物使用的作用。方法2008年6月89例骨折住院患者按药师是否参与用药决策分为2组,药师参与指导用药组(A组)45例,医生经验用药组(B组)44例。根据设计的调查表,按统一方法、标准和内容,对药师参与指导临床使用抗菌药物的情况进行统计分析。结果2组患者均使用抗菌药物。A组患者使用单一、2联、3联及以上抗菌药物者分别占81.40%、16.28%、2.30%,B组分别占43.48%、47.83%、8.69%,2组比较差异有统计学意义(P均<0.01)。人均住院费用、人均药费、人均抗菌药费A组均低于B组。对DDD、DDDs及DUI值分析显示,A组用药更合理,无滥用抗菌药物情况。结论临床药师参与指导用药的抗菌药物使用成本明显降低,临床用药更合理。应重视临床药学工作,充分发挥临床药师在抗菌药物使用中的决策、督导、宣传和教育作用,达到合理应用抗菌药物的目的。
Objective To evaluate the role of clinical pharmacists in guiding the use of orthopedic antibiotics. Methods Eighty-nine patients with fracture in June 2008 were divided into two groups according to whether the pharmacist participated in the medication decision-making. Among them, 45 pharmacists participated in the medication group (A group), and 44 experienced the doctor medication group (B group). According to the design of the questionnaire, according to a unified method, standards and content of pharmacists involved in guiding the clinical use of antimicrobial agents for statistical analysis. Results Both groups of patients used antimicrobial drugs. The patients in group A occupied 81.40%, 16.28% and 2.30%, respectively, while those in group B accounted for 43.48%, 47.83% and 8.69%, respectively. The difference between the two groups was statistically significant (P All <0.01). Per capita hospitalization costs, per capita drug costs, per capita antimicrobial drug costs were lower in group A than in group B. Analysis of DDD, DDDs and DUI values showed that the use of drugs in group A was more rational and there was no abuse of antimicrobial drugs. Conclusion The cost of antibacterials used by clinical pharmacists to guide the medication significantly reduced, and the clinical medication was more reasonable. Should pay attention to clinical pharmacy work, give full play to clinical pharmacists in the use of antibacterial drugs in the decision-making, supervision, publicity and education, to achieve the rational use of anti-bacterial drugs.