肢端黑素瘤是指发生在掌跖、指趾末端、甲皱襞或甲床的一种特殊的恶性黑素痛。它的发生部位特殊且隐匿,侵袭生长迅速,早期易发生转移,预后差。现将我们所见12例肢端黑素瘤报告如下。临床资料12例中男性7例,女性5例,年龄43～79岁,病程1～10年。皮疹发生在足底1例,表现为深在溃疡,溃疡边缘有黑色肿块。发生在足趾6例,趾间黑斑,趾端变黑、肿大、畸形,个别肿块周围有卫星灶。指甲4例,趾甲1例,表现为甲黑色条纹增宽,甲变形或甲下出现黑 Acral melanoma refers to a special type of malignant melanin pain that occurs in the palmoplantar, distal toes, creases, or nail beds. The site of its occurrence is special and hidden, the invasion and growth are rapid, the metastasis is easy to occur in the early stage, and the prognosis is poor. We now report 12 cases of acral melanoma as follows. The clinical data of 12 cases were 7 males and 5 females, aged from 43 to 79 years and duration of 1 to 10 years. The rash occurred in the sole of the foot in one case and was characterized by a deep ulceration with a black bump on the edge of the ulcer. Occurred in the toe 6 cases, dark spots between the toes, toe end black, swollen, deformed, there are satellite lesions around individual tumors. 4 cases of nails and 1 case of toenail, showing broadening of the nail-black stripes, a distorted nail, or black under the nail