目的观察阿奇霉素对肺炎患儿C反应蛋白(CRP)及血沉(ESR)影响。方法 85例确诊为支气管肺炎患儿分为治疗组及对照组,经血液检查对比阿奇霉素治疗组肺炎患儿CRP及ESR变化。结果肺炎患儿CRP及ESR均较前下降,P<0.05,差异有统计学意义。结论阿奇霉素对肺炎患儿治疗有较好的临床疗效,可降低影响肺炎炎症病理生理的CRP及ESR,可作为临床一线用药。 Objective To observe the effect of azithromycin on C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in children with pneumonia. Methods 85 children diagnosed as bronchial pneumonia were divided into treatment group and control group. The changes of CRP and ESR in children with pneumonia after azithromycin treatment were compared by blood test. Results The CRP and ESR in children with pneumonia were lower than before, P <0.05, the difference was statistically significant. Conclusions Azithromycin has a good clinical curative effect on children with pneumonia and can reduce the CRP and ESR that affect the pathophysiology of pneumonia. It can be used as first-line medicine in clinic.