1例胰头肿块型慢性胰腺炎反复发作患者，病史长，反复腹痛腹胀、恶心呕吐，多家医院非手术治疗未见明显好转。经中南大学湘雅三医院消化内科、肝胆胰外科、肿瘤科、病理科、放射科等多学科团队诊治，对该患者实施胰十二指肠切除术，完全切除引起疼痛的病灶，未留有因慢性炎症引起癌变的组织学基础，手术安全性大大提高，未发生明显并发症。“,”One patient with recurrent attacks of pancreatitis and pancreatic head mass had a long history of recurrent abdominal pain, abdominal distension, nausea and vomiting, and no significant alleviations were observed under non-surgical treatment in many hospitals. After the diagnosis and treatment by the multidisciplinary team of gastroenterology, hepatobiliary and pancreatic surgery, oncology, pathology, radiology and other departments of Third Xiangya Hospital of Central South University, the patient underwent pancreaticoduodenectomy to completely remove the painful lesion, without leaving histological basis for canceration caused by chronic inflammation. The safety of the surgery was greatly improved and no obvious complications were observed.