论文部分内容阅读
目的探讨妊娠高血压综合征(妊高征)患者瘦素水平变化及其与血压、尿蛋白的关系。方法回顾性分析我院2010年1-10月收治的36例妊高症孕妇为观察组,并随机选用同期收治的正常孕妇20例为对照组,比较两组血清瘦素水平、尿蛋白、血压关系。结果观察组瘦素在妊高症中度及重度与对照组相比较显著升高,P<0.05。SBP两组相比较,轻度、中度、高度三组均有显著性意义(P<0.05,P<0.01)。DBP两组相比较,高度妊高症组有显著性意义,(P<0.05)。尿蛋白两组相比较,轻度、中度、高度三组均有显著性意义(P<0.05,P<0.01)。结论妊高征孕妇血清瘦素水平较正常孕妇显著升高,其中相应血压及尿蛋白指标升高,检测其变化对判断患者病情及预后有一定价值。
Objective To investigate the changes of leptin level in patients with pregnancy induced hypertension (PIH) and its relationship with blood pressure and urinary protein. Methods A retrospective analysis of 36 pregnant women with PIH admitted in our hospital from January to October in 2010 was taken as observation group and 20 normal pregnant women treated in the same period were selected as control group. Serum leptin level, urine protein, blood pressure relationship. Results In observation group, leptin was significantly higher in moderate and severe pregnancy-induced hypertension than in control group (P <0.05). Compared with SBP group, there were significant differences in mild, moderate and high three groups (P <0.05, P <0.01). Compared with DBP, there was a significant difference between the two groups (P <0.05). There was significant difference between the two groups (P <0.05, P <0.01). Conclusions The serum leptin levels of pregnant women with PIH are significantly higher than those of normal pregnant women, and the corresponding blood pressure and urinary protein index are elevated. It is of some value to detect the changes of serum leptin levels in patients’ condition and prognosis.