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糖尿病是一种常见病,各种族人群的发病率均在1～20％左右,并且随年龄增加而增加,65岁以上的发病率可高达5％。糖尿病有胰岛素依赖性糖尿病(IDDM)和非胰岛素依赖性糖尿病(NIDDM)两种类型。IDDM发病年龄小,发病率低,仅占糖尿病患者总数的10～15％,NIDDM一般在40岁以后发病,发病率较高,占糖尿病患者总数的85～90％。对挛生子的研究表明,NIDDM有很强的遗传现象,但还未发现有肯定的同NIDDM相关的基因标志。一般认为NIDDM的发病原因是颇为复杂的,多元性的。推测有两种可能:一是由于胰岛素分子结构异常,原有
Diabetes is a common disease, the incidence of all ethnic groups are about 1 to 20%, and increased with age, the incidence of 65 years of age can be as high as 5%. Diabetes has two types of insulin-dependent diabetes mellitus (IDDM) and non-insulin-dependent diabetes mellitus (NIDDM). IDDM age of onset is small, the incidence is low, accounting for only 10 to 15% of the total number of diabetic patients, NIDDM generally after the onset of the age of 40, the incidence is higher, accounting for 85 to 90% of the total number of diabetic patients. Studies on the twin have shown that NIDDM has a strong genetic profile but no positive genetic markers associated with NIDDM have been found. Generally believed that the causes of NIDDM is quite complex and diverse. Speculated that there are two possibilities: First, due to abnormal molecular structure of insulin, the original