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目的:探讨早产儿视网膜病的高危因素并提出预防措施。方法:对2006～2007年出生于广东省内部分三甲医院、出生体重<2000g及胎龄<37周早产儿进行眼底检查,分析ROP发生的高危因素。结果:在完成眼底检查的1094例早产儿中,发生ROP的患儿为139例(12.7%)。单因素分析显示,ROP的发生与出生体重、出生胎龄、吸氧浓度、低氧血症、感染、输血等因素相关。结论:ROP的发生主要与低出生体重、小出生胎龄及吸氧浓度相关,同时低氧血症、感染及输血也对ROP的发生产生影响。
Objective: To investigate the risk factors of retinopathy in premature infants and to propose preventive measures. Methods: The fundus examination of premature infants born at some of the top three hospitals in Guangdong province from 2006 to 2007 with birth weight <2000g and gestational age <37 weeks was carried out to analyze the risk factors of ROP. Results: Among 1094 preterm infants who underwent fundus examination, 139 (12.7%) had ROP. Univariate analysis showed that the incidence of ROP and birth weight, gestational age, oxygen concentration, hypoxemia, infection, blood transfusion and other factors. Conclusion: The incidence of ROP is mainly associated with low birth weight, small gestational age and oxygen inhalation concentration. Hypoxemia, infection and blood transfusions also have an impact on the occurrence of ROP.