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对４７例哮喘急性发作患者，就肾素－血管紧张素－醛固酮含量与中医辨证分型关系进行研究，发现哮喘组肾素活性（ＰＲＡ）含量高于对照组（Ｐ＜０．０１）；血管紧张紊Ⅱ（ＡＴ－Ⅱ）以寒哮组增加最为明显（Ｐ＜０．０１）；醛固酮（ＡＬＤ）热哮组低于对照组（Ｐ＜０．０５）。哮喘组ＰＲＡ与ＰａｃＯ＿２呈负相关，热哮组ＡＬＤ与ＰａＣＯ＿２呈正相关。并发现ＰＲＡ，ＡＴ－Ⅱ随病情加重而升高。死亡者ＰＲＡ水平高于缓解患者（Ｐ＜０．０１）。提示：ＰＲＡ可作为哮喘患者预后判断及疗效考核指标。
In 47 patients with acute exacerbation of asthma, the relationship between renin - angiotensin - aldosterone content and TCM syndrome differentiation was studied. The results showed that the renin activity (PRA) in asthma group was higher than that in control group (P <0.01) Tension turbulence (AT-Ⅱ) was the most significant increase in the group of cold-induced asthma (P <0.01), aldosterone (ALD) was lower in the heat-asthma group than the control group (P <0.05). There was a negative correlation between PRA and PacO_2 in asthma group, and positive correlation between ALD and PaCO_2 in heat asthma group. And found that PRA, AT-Ⅱ increased with the exacerbations. The level of PRA in the deceased was higher than that in the relieved patients (P <0.01). Tip: PRA can be used as a prognostic indicator of asthma patients and indicators of efficacy.