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中枢神经介质(Neurotransmitter)的研究是探讨生命活动脑化学机制的重要研究环节。目前比较肯定并对其通路了解比较清楚的有去甲肾上腺素(Norepinephrine,NE)、多巴胺(Dopamine,DA)、5-羟色胺(Serotonin,5-HT)和乙酰胆碱。了解中枢生物胺介质的变化,对探索它们在生命活动中的作用机制十分必要。自1973年Kissinger等把电化学检测器与高效液相色谱结合测定儿茶酚胺以来,由于此方法快速、灵敏、经济,受到分析化学和神经生物学工作者的关
Neurotransmitter research is an important part of the research on the brain chemical mechanism of life activity. At present, Norepinephrine (NE), Dopamine (DA), Serotonin (5-HT) and acetylcholine are more clearly understood and their pathways are known. Understanding the changes in CNBMs is essential to explore their mechanisms of action in life. Since 1973, Kissinger and other electrochemical detectors and high performance liquid chromatography combined with the determination of catecholamines, since this method is fast, sensitive, economical, analytical chemistry and neurobiology workers off