重症联合免疫缺陷病Severe Comb—ined Immuno deficiency(SCID),自Glanzmann＆ Riniker 50年以“特发性淋巴细胞萎缩”的命名报告以来,已逐渐引起医学界的重视,报导的病例逐年增多,世界上相继报导200余例。我国报导的病例则以种痘后泛发性痘疹伴有免疫球蛋白减少的资料为主,共余十例。本病一般无近缘结婚关系。男性多于女性,发病年令多在一岁以内。病儿对病毒、细菌及真菌极敏感。常表现感染及顽固性腹泻和 Severe combined immunodeficiency disease Severe Comb-ined Immuno deficiency (SCID), has been attracting much attention in the medical community since Glanzmann & Riniker’s 50-year report of “idiopathic lymphocyte atrophy.” The reported cases have been increasing year by year. More than 200 cases have been reported. The cases reported in China are based on the data of generalized pox measles with immunoglobulin reduction after vaccination, with a total of 10 cases. The disease is generally not related to the marriage. More men than women, more than one year of age onset. Sick children are very sensitive to viruses, bacteria and fungi. Common manifestations of infection and stubborn diarrhea and