恶性胸腔积液是由恶性肿瘤胸膜转移或原发于胸膜的恶性肿瘤所致,多为血性,生长迅速,不易控制,且呈进展性加重,因胸水而致胸痛、呼吸困难、重度呼吸衰竭,故预后差。生物免疫治疗用于胸腔内注射,既能诱导产生免疫效应细胞而发挥抗肿瘤作用,又可使胸膜产生化学性炎症粘连而使胸膜腔闭塞,且对机体刺激轻微,无骨髓抑制和消化 Malignant pleural effusion is caused by malignant pleural metastasis or primary malignant tumor in the pleura, mostly bloody, rapid growth, not easy to control, and showed progressive aggravated, due to pleural effusion caused by chest pain, difficulty breathing, severe respiratory failure, So the prognosis is poor. Bioimmunotherapy for intrathoracic injection, both to produce immune effector cells and exert anti-tumor effect, but also make the pleural inflammation of the chemical adhesions and the pleural cavity occlusion, and the body to stimulate a minor, no bone marrow suppression and digestion