卵巢上皮性癌(EOC)是病死率最高的妇科恶性肿瘤,大多数患者在经过初始治疗后仍将复发,而复发是其主要死因。EOC已成为西方国家女性癌症第五大最常见死亡原因~[1]。在过去的20年里,随着对EOC起源认识的提高,以及铂类为基础的有效化疗药物的出现,疾病的短期控制得到了改善,但是EOC的总生存率远低于其他实体恶性肿瘤,5年总生存率并没有得到明显的提高,以铂 Epithelial ovarian cancer (EOC) is the most fatally malignant gynecological cancer, and most patients will relapse after initial treatment, with relapse as the leading cause of death. EOC has become the fifth most common cause of death in women in Western countries ~ [1]. Over the past two decades, short-term control of the disease has improved with the increased awareness of the origin of EOCs and the emergence of potent chemotherapeutic drugs based on platinum, but the overall survival of EOCs is much lower than that of other solid malignancies, 5-year overall survival rate has not been significantly improved to platinum