小剂量皮质类固醇激素巳广泛用于严重的各型复发性阿弗它溃疡,糜烂型扁平苔癣, 良性粘膜类天疱疮以及多形红斑。应用类固醇治疗复发性阿弗它溃疡的理论根据是早期的组织学变化为迟发超敏反应的表现,以及在溃疡出现后至少2—3天内的早期阶段出现对口腔粘膜致敏的淋巴细胞大量增加。由于复发性阿弗它溃疡患者的淋巴细胞对上皮 Low-dose corticosteroids have been widely used in severe recurrent aphthous ulcers, erosive lichen planus, benign mucocutaneous pemphigoid and erythema multiforme. The rationale for the use of steroids in the treatment of recurrent aphthous ulcers is that early histological changes are manifestations of delayed hypersensitivity reactions as well as large numbers of lymphocytes sensitized to the oral mucosa at an early stage within at least 2-3 days after ulcer onset increase. Due to recurrent aphthous ulcer in patients with lymphocytes on the epithelium