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目的探讨苗药酢酱草等治疗Ⅲ型前列腺炎作用机制,将苗药治疗CNBP的作用机制推进到分子水平。方法将60例CNBP患者分为2组,每组30例,分别采用苗药、中成药进行治疗,并对治疗前后前列腺液常规、IL-1β、TNF-α等指标进行统计分析。结果治疗后苗药组IL-1β、TNF-α的水平较对照组显著下降,患者临床症状明显改善。结论苗药酢酱草等能明显改善CNBP患者症状、显著降低患者前列腺液中IL-1β、TNF-α水平,是较为有效的治疗CNBP临床经验方。
Objective To explore the mechanism of action of Miao medicine, Agkistrodon przew and so on, on the treatment of type Ⅲ prostatitis. The mechanism of action of Miao drug on CNBP was advanced to the molecular level. Methods Sixty patients with CNBP were divided into two groups (n = 30 in each group). The patients were treated with Miao and proprietary Chinese medicines respectively. The levels of routine, IL-1β and TNF-α in prostatic fluid before and after treatment were statistically analyzed. Results After treatment, the levels of IL-1β and TNF-α in Miao drug group were significantly lower than those in control group, and the clinical symptoms were significantly improved. Conclusion Miao medicine Agnus solanacearum can significantly improve the symptoms of CNBP patients, and significantly reduce the level of IL-1β and TNF-α in prostatic fluid of patients. It is a more effective clinical trial of CNBP.