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目的:分析颅脑核磁表观弥散系数(ADC)对早期脑损伤的评估价值。方法:选取本院2014年1月至2015年1月收治的35例外伤性脑损伤患者为观察组,同期选取正常人35例为对照组。对两组病例行磁共振扫描,采用弥散加权成像(DWI)检查后计算感兴趣区(ROI)ADC值,分析两组病例ADC值的差异,对脑损伤患者病情进行初步判断。结果:(1)观察组DWI异常高信号灶状区域ADC值为(0.98±0.05)×10~(-3)mm~2/s低于对照组(1.27±0.08)×10~(-3)mm~2/s,差异具有统计学意义(P<0.05);(2)观察组DWI异常高信号弥漫区域ADC值为(0.95±0.04)×10~(-3)mm~2/s低于对照组(1.26±0.11)×10~(-3)mm~2/s,差异具有统计学意义(P<0.05);(3)观察组DWI异常高信号区域相对表观扩散系数(r ADC)值为(0.51±0.02)×10~(-3)mm~2/s高于对照组(0.35±0.01)×10(-3)mm~2/s,差异具有统计学意义(P<0.05)。结论:颅脑核磁ADC对早期脑损伤的评估具有重要意义。
Objective: To evaluate the value of brain magnetic apparent diffusion coefficient (ADC) in brain evaluation of early brain injury. Methods: 35 cases of traumatic brain injury admitted from January 2014 to January 2015 in our hospital were selected as the observation group. 35 normal subjects were selected as the control group. MRI scan was performed on the two groups of patients. Diffusion-weighted imaging (DWI) was used to calculate the ADC value of ROI. The differences of ADC values between the two groups were analyzed. The initial judgment was made on the patients with brain injury. Results: (1) The ADC value of focal area with high DWI abnormality in observation group was (0.98 ± 0.05) × 10 -3 mm 2 / s lower than that in control group (1.27 ± 0.08) × 10 -3 mm2 / s, the difference was statistically significant (P <0.05); (2) The ADC value of diffuse area with high DWI abnormality in the observation group was (0.95 ± 0.04) × 10 -3 mm 2 / s (1.26 ± 0.11) × 10 ~ (-3) mm ~ 2 / s, the difference was statistically significant (P <0.05); (3) The relative apparent diffusion coefficient (r ADC) (0.51 ± 0.02) × 10 ~ (-3) mm ~ 2 / s was significantly higher than that of the control group (0.35 ± 0.01) × 10 (-3) mm ~ 2 / s and the difference was statistically significant (P0.05) . Conclusion: Cerebral nuclear magnetic resonance ADC is of great importance in the assessment of early brain injury.