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目的分析深圳市小儿急性呼吸道感染病毒病原检测结果,为临床提供病毒病原学诊断依据。方法选择2005年6月至2007年6月深圳市急性呼吸道感染患儿,取其鼻咽分泌物,进行多功能悬浮式点阵病毒分子生物学检测,筛查8种呼吸道病毒抗原,对阳性检测标本进行分析。结果病毒检测的总阳性率为57.2%(413/720),FIV-A、RSV和PIV-Ⅲ的阳性率为81.4%(336/413);不同季节病毒阳性率不同;3岁以下小儿阳性率83.3%(344/413);病毒检测阳性率支气管哮喘患儿低于上呼吸道感染、支气管炎、肺炎、毛细支气管炎患儿。结论深圳市小儿呼吸道感染以病毒性为主,FIV-A、RSV、PIV-Ⅲ为主要病原;小儿呼吸道感染病毒检测,为动态了解其流行特征及规律提供了重要的依据,对呼吸道疾病的诊断和治疗有着非常重要的指导意义。
Objective To analyze the results of virus pathogen detection in children with acute respiratory infection in Shenzhen and provide the basis for the diagnosis of viral etiology. Methods From June 2005 to June 2007, children with acute respiratory infection in Shenzhen were collected for nasopharyngeal secretions, molecular detection of multi-functional floating dot virus and screening for eight kinds of respiratory virus antigens. Positive detection Specimens were analyzed. Results The positive rate of virus detection was 57.2% (413/720). The positive rate of FIV-A, RSV and PIV-Ⅲ was 81.4% (336/413). The positive rate of virus in different seasons was different. The positive rate of children under 3 years old 83.3% (344/413). The positive rates of virus detection in children with bronchial asthma were lower than those in children with upper respiratory tract infection, bronchitis, pneumonia and bronchiolitis. Conclusions Children with respiratory tract infection in Shenzhen are virus-based, and FIV-A, RSV and PIV-Ⅲ are the major pathogens. Detection of respiratory viruses in children provides an important basis for understanding their epidemiological features and rules dynamically. Diagnosis of respiratory diseases And treatment has a very important guiding significance.