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目的探讨超声实时组织弹性成像(URTE)定量分析对肝脏纤维化程度的诊断和鉴别诊断价值。方法采用URTE定量分析2015年12月至2016年12月200例正常人的肝纤维化指数(LF Index),并以此为正常标准,分析150例慢性乙型病毒性肝炎(CHB)患者的肝脏纤维化程度,并与病理学诊断结果比较。结果在150例CHB患者中,病理结果显示94例为阳性,56例为阴性。以正常肝脏LF Index为标准,URTE定量分析诊断肝脏纤维化的灵敏度为94.68%(89/94),特异度为89.29%(50/56),准确度为92.67%(139/150);以LF Index>1.8573为阳性标准,URTE的ROC曲线下面积为0.921(95%CI:0.861~0.981)。结论 URTE定量分析可鉴别诊断正常肝脏与肝脏纤维化,并有助于评估肝纤维化程度。
Objective To investigate the value of real-time ultrasonography elastography (URTE) in the diagnosis and differential diagnosis of liver fibrosis. Methods URTE was used to quantitatively analyze the liver fibrosis index (LF Index) of 200 normal subjects from December 2015 to December 2016 as the normal standard. The liver of 150 patients with chronic hepatitis B (CHB) The degree of fibrosis, and compared with the pathological diagnosis. Results In 150 CHB patients, pathological results showed that 94 cases were positive and 56 cases were negative. According to the normal liver LF index, URTE quantitative analysis of liver fibrosis sensitivity was 94.68% (89/94), the specificity was 89.29% (50/56), the accuracy was 92.67% (139/150) Index> 1.8573 was positive, and the area under the ROC curve for URTE was 0.921 (95% CI: 0.861-0.981). Conclusion URTE quantitative analysis can differentiate normal liver and liver fibrosis, and help to assess the degree of liver fibrosis.