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目的 :了解充血性心力衰竭 (CHF)住院患者一般情况、病因、药物治疗、转归及死亡等 10年间变化。方法 :将入选的 6 4 5例CHF患者 ,分成 1988～ 1990年段组 (A组 )和 2 0 0 0～ 2 0 0 2年段组 (B组 )。分别对两组住院病历进行回顾性分析及比较。结果 :①入选的 6 4 5例患者中 ,男 371例、女 2 74例 ,平均年龄 (6 5 .4± 18.3)岁～ (6 7.2± 12 .5 )岁 ;B组较A组病程 [(5 8.3± 6 3.2 )∶(95 .6± 77.3)个月 ,P <0 .0 1]和住院时间 [(2 0 .8± 2 4 .6 )∶(30 .5±32 .5 )d ,P <0 .0 1]缩短。②心力衰竭 (心衰 )病种主要是冠心病、风湿性瓣膜病及原发性高血压 (EH) ,10年间冠心病已从 34.5 %上升到 5 6 .0 % (P <0 .0 1) ,EH从 10 .3%升至 15 .1% (P >0 .0 5 ) ,风湿性瓣膜病由 30 .6 %下降到16 .2 % (P <0 .0 1)。③住院期间治疗心衰的药物仍以利尿剂、硝酸酯类和洋地黄类制剂为主 ,洋地黄类制剂的使用有下降的趋势 (4 3.4 %∶39.0 % ,P >0 .0 5 ) ,β受体阻滞剂 (8.8%∶2 1.1% ,P <0 .0 1)和血管紧张素转换酶抑制剂 (2 4 .1%∶6 0 .9% ,P <0 .0 1)的应用明显上升。④住院期间症状明显改善率升高 (19.9%∶2 3.3% ,P >0 .0 5 ) ,住院病死率明显降低 (12 .4 %∶6 .3% ,P <0 .0 5 )。结论 :10年间 ,住院的CHF
Objective: To understand the general situation of hospitalized patients with congestive heart failure (CHF), etiology, medication, outcome and death over 10 years. Methods: A total of 645 CHF patients were divided into two groups: group A (1988-1990) and group B (group B) between 2000 and 2002. The two groups of hospitalized patients were retrospectively analyzed and compared. RESULTS: Among the 645 selected patients, 371 were male and 742 were female, with an average age of (6.54 ± 18.3) years to (62.2 ± 12.5) years; (5 8.3 ± 6 3.2): (95.6 ± 77.3) months, P <0.01, and length of stay [(20.8 ± 24.4): (30.5 ± 32.5) d, P <0. ② heart failure (heart failure) is mainly coronary heart disease, rheumatic valvular disease and essential hypertension (EH), 10 years of coronary heart disease has risen from 34.5% to 56.0% (P <0 1 ), EH increased from 10.3% to 15.1% (P> 0.05), rheumatic valvular disease decreased from 30.6% to 16.2% (P <0.01). (3) Drugs used to treat heart failure during hospitalization were still mainly diuretics, nitrates and digitalis preparations, and the use of digitalis preparations showed a decreasing tendency (34.4% vs 39.0%, P> 0.05) The application of blockers (8.8%: 2.1 1.1%, P <0.01) and angiotensin converting enzyme inhibitors (24.1%: 6.09%, P <0.01) Significantly increased. ④ Significant improvement of symptoms during hospitalization (19.9% vs2.33%, P> 0.05), hospital mortality was significantly reduced (12.4%: 6.3%, P <0.05). Conclusions: Hospitalized CHF for 10 years