论文部分内容阅读
支气管反应亢进或反应过强指的是气道对物理、化学和药理学刺激的极度敏感。正常人对吸入物有支气管过度收缩反应者占3％;症状性哮喘的病人则为100％;有哮喘史但无症状者为70％;患过敏性鼻炎以及不少患慢性支气管炎和肺气肿的病人为22％。一、机理: 决定气道反应程度的因索还不清楚。几种可能性假设可解释它的病理生理,而涉及的因素很可能不只一种。 (一)气道平滑肌的改变:在探索气道反应亢进单一的原发机理时,常集中注意气道平滑肌以及假想动物组织的某些改变。不过,解释这些研究的结果有困难,因为动物不具备人类疾病非特异性气道反应亢进的特征。少数死于其它原因的哮喘病人,又没有活体
Bronchial hyperresponsiveness or hyperresponsiveness refers to the extreme sensitivity of the airways to physical, chemical, and pharmacological stimuli. Normal inhaled bronchial hyperresponsiveness accounted for 3%; symptomatic asthma patients were 100%; history of asthma but asymptomatic 70%; suffering from allergic rhinitis and many chronic bronchitis and lung disease Swollen patients was 22%. First, the mechanism: the decision of the degree of airway reaction is not clear. Several possible assumptions explain its pathophysiology, and the factors involved are likely to be more than one. (A) changes in airway smooth muscle: In exploring the primary mechanism of airway hyperfunction, often pay attention to some changes in airway smooth muscle and imaginary animal tissues. However, explaining the results of these studies is difficult because animals do not possess the characteristics of nonspecific airway hyperresponsiveness to human disease. A handful of asthmatics who died of other causes did not have any living body