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川芎嗪是从川芎中提取的生物碱单体,是川芎的主要活性成分之一,具有抗氧化、拮抗钙超载、抑制细胞凋亡、抗炎、抗血栓改善微循环、减轻缺血/再灌注损伤等药理作用。将川芎嗪添加到胰腺、肾脏、肝脏、肺及周围神经等组织、器官保存液中,有利于减轻组织、器官的缺血和再灌注损伤,从而改善组织、器官的保存效果及移植预后。
Ligustrazine is an alkaloid monomer extracted from Ligusticum chuanxiong. It is one of the main active components of Ligusticum chuanxiong. It has antioxidation, antagonizes calcium overload, inhibits apoptosis, anti-inflammatory, antithrombotic, improves microcirculation, and reduces ischemia/reperfusion. Damage and other pharmacological effects. The addition of tetramethylpyrazine to pancreas, kidney, liver, lung and peripheral nerve tissue and organ preservation solution will help reduce tissue and organ ischemia and reperfusion injury, thereby improving the preservation effect of tissues and organs and the prognosis of transplantation.