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目的观察内镜下钛夹联合黏膜注射治疗急性非静脉曲张性上消化道出血的临床效果。方法将60例急性非静脉曲张性上消化道出血患者随机分为黏膜注射止血组、钛夹止血组和钛夹止血联合黏膜注射止血组,各20例。对比3组治疗后即刻止血效果和72h再出血率。结果钛夹止血联合黏膜注射止血组即时止血有效率明显高于黏膜注射止血组和钛夹止血组,72h再出血率明显低于黏膜注射止血组和钛夹止血组,差异均有统计学意义(P<0.05)。黏膜注射止血组和钛夹止血组即时止血有效率及治疗后72h再出血率比较差异均无统计学意义(P>0.05)。结论内镜下钛夹止血联合黏膜注射止血治疗急性非静脉曲张性上消化道出血的止血效果好,72h再出血率低,值得推广应用。
Objective To observe the clinical effect of endoscopic titanium clip combined mucosal injection in the treatment of acute non-variceal upper gastrointestinal bleeding. Methods Sixty patients with acute non-variceal upper gastrointestinal bleeding were randomly divided into mucosal injection hemostasis group, titanium clamp hemostasis group and titanium clamp hemostasis combined with mucosal injection hemostasis group, 20 cases in each group. Compare the three groups immediately after treatment hemostatic effect and 72h rebleeding rate. Results The effective rate of immediate hemostasis was significantly higher than that of mucosal injection and titanium clip-stop bleeding, and the rate of rebleeding at 72 hours was significantly lower than that of mucosal injection and titanium clip-stop bleeding P <0.05). There was no significant difference between the mucosal injection hemostasis group and the titanium clamp group in immediate hemostasis and the rebleeding rate at 72 hours after treatment (P> 0.05). Conclusion Endoscopic titanium hemostasis combined mucosal injection of hemostasis in the treatment of acute non-variceal hemorrhage bleeding effect, 72h rebleeding rate is low, it is worth promoting the application.