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目的:探讨腹腔镜半肝切除术中肝中静脉(MHV)显露的安全性及可行性。方法:回顾性分析2017年6月～2019年12月南京医科大学附属常州第二人民医院肝胆胰外科行腹腔镜下半肝切除58例患者的临床资料，根据术中有无显露MHV将患者分为显露组和非显露组，对比两组患者的一般情况、手术时间、术中出血量、术后并发症、术后第3天丙氨酸氨基转移酶(ALT)、术后住院天数等指标。结果:腹腔镜下半肝切除的58例患者中男性36例，女性22例，年龄22.0～75.0(49.8±12.1)岁，MHV显露组患者30例，非显露组患者28例。两组患者年龄、Child-Pugh评分、疾病谱等方面的一般资料差异无统计学意义(n P>0.05)。共有3例患者中转开腹，其中显露组2例，原因为严重的COn 2气体栓塞导致循环不稳和不易控制的术中出血各1例，非显露组1例为术中较多出血而中转开腹。显露组患者手术时间较非显露组手术时间长[(240.8±80.6)min比(185.8±50.6) min]，差异有统计学意义(n P0.05). Three patients were converted to laparotomy, with 2 in the exposure group. The reasons for conversion were severe COn 2 gas embolism causing circulatory instability (n n=1) and intraoperative bleeding which was difficult to control (n n=1). Of the remaining 1 patient in the non-exposed group, conversion to laparotomy was done because of intraoperative bleeding. The operation time of the exposed group was significantly longer than the non-exposed group [(240.8±80.6) min vs (185.8±50.6) min, n P<0.05]. The ALT of the exposed group was significantly lower than the non-exposed group on post-operative day 3 [(150.8±80.6) U/L vs (287.6±110.2) U/L,n P0.05).n Conclusions:Exposure of MHV allowed precise anatomical hemihepetectomy and was safe and feasible. Difficulties of this operation were found to be mainly related to how to find the trunk of MHV quickly and how to deal with intraoperative hemorrhage effectively.