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目的观察苦参凝胶联合雌三醇软膏治疗萎缩性阴道炎的临床疗效。方法将120例萎缩性阴道炎患者随机分为苦参凝胶组(A组)、雌三醇组(B组)、联合用药组(C组),分别给予相应治疗,疗程8天。分别于治疗后3天和30天评定临床疗效。结果治疗结束后3天,三组总有效率均为100%;C组愈显率高于A组和B组(P<0.05)。治疗后30天随访,C组总有效率和愈显率均高于A组和B组(P<0.05)。结论苦参凝胶和雌三醇软膏联合应用治疗萎缩性阴道炎具有协同作用,远期疗效良好。
Objective To observe the clinical effect of kushen gel combined with estriol ointment in the treatment of atrophic vaginitis. Methods A total of 120 patients with atrophic vaginitis were randomly divided into two groups: A group (group A), estriol group (B group) and combination group (group C). Clinical efficacy was assessed 3 and 30 days after treatment, respectively. Results Three days after the end of treatment, the total effective rate of the three groups was 100%. The cure rate of group C was higher than that of group A and B (P <0.05). At 30 days after treatment, the total effective rate and the cure rate in group C were significantly higher than those in group A and group B (P <0.05). Conclusion The combination of kushen gel and estriol ointment has a synergistic effect in the treatment of atrophic vaginitis, and the long-term curative effect is good.