论文部分内容阅读
作者有一例复发性口底鳞癌患者,因患肺结核接受异菸肼合并氨甲喋呤(MTX)及环磷酰胺治疗,获得长时期肿瘤完全消退。这个十分满意的结果提出了几个问题:该病例结核菌素试验为强阳性,是否同时也有迟发性过敏反应,从而增进了化疗药物的良好疗效?能否应用卡介苗接种子其它病人以增加化疗效果?因为异菸肼在某些实验中证实有破坏脱氧核糖核酸(DNA)的能力,是否是使病员长期维持疗效的原因?于是作者
One case of recurrent squamous cell carcinoma of the mouth was treated with isoniazid combined with methotrexate (MTX) and cyclophosphamide for recurrent squamous cell carcinoma of the mouth. This very satisfactory result raises several questions: Is this case a strong positive tuberculin test, is it also delayed onset of allergic reactions at the same time, thereby enhancing the good efficacy of chemotherapy drugs? Can be used to vaccinate other patients with BCG to increase chemotherapy Effect? Because isoniazid in certain experiments has confirmed the ability to destroy DNA, is it the reason for the patient to maintain long-term efficacy? Then the author