Colville等报道了英国诺丁汉地区数例与麻疹、腮腺炎和风疹疫苗(MMR)相关的脑膜炎病例。自1989年以来,作者从接种MMR后腮腺炎和脑膜炎病例、无症状接种者以及与接种无关的腮腺炎病例分离腮腺炎病毒。用聚合酶链反应(PCR)和编码融合蛋白的病毒基因组的小区段作核苷酸序列分析,对上述分离株进行鉴定。作者对世界各地的80多株病毒作了鉴 Colville et al. Reported several cases of meningitis associated with measles, mumps and rubella vaccine (MMR) in Nottingham, UK. Since 1989, the authors isolated mumps virus from cases of mumps and meningitis after vaccination with MMR, asymptomatic vaccinates, and mumps unrelated to vaccination. The above isolates were identified by polymerase chain reaction (PCR) and nucleotide sequencing of the small segment of the viral genome encoding the fusion protein. The author of more than 80 strains of viruses around the world made a lesson