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急性早幼粒细胞白血病 (APL) ,具有特异性的染色体易位 t(1 5∶ 1 7)及 PML/RARa融合基因。在细胞遗传学 (MIC)分型的基础上 ,采用逆转录聚合酶链反应 (RT- PCR)技术 ,检测 APL的 PML/RARa融合基因的 m RNA,可以用来诊断或鉴别诊断 ,同时也可以进行微量残留白血病细胞 (MRLC)的
Acute promyelocytic leukemia (APL) has a specific chromosomal translocation t(15:17) and PML/RARa fusion gene. On the basis of cytogenetics (MIC) typing, the use of reverse transcriptase polymerase chain reaction (RT-PCR) technology to detect the mPL of the APL PML/RARa fusion gene can be used for diagnosis or differential diagnosis. Performing trace residual leukemia cells (MRLC)