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目的回顾分析腺苷蛋氨酸在肝癌TACE围手术期治疗中的疗效。方法将经TACE治疗的70例患者分为腺苷蛋氨酸治疗组和还原型谷胱甘肽治疗组,分别对其术前术后肝功指标进行化验分析。结果两组病例中转氨酶变化无统计学差异,但腺苷蛋氨酸组患者碱性磷酸酶,总胆红素,γ-GT转移酶升高幅度均小于对照组,其中胆红素,碱性磷酸酶指标控制效果明显。结论腺苷蛋氨酸在TACE围术期的治疗中,保护肝功效果明显,尤其对合并胆红素升高的患者有更好疗效。
Objective To retrospectively analyze the effect of adenosine methionine in the perioperative treatment of TACE of liver cancer. Methods TACE treatment of 70 patients were divided into adenosyl methionine treatment group and reduced glutathione treatment group, respectively, the preoperative and postoperative liver function tests were analyzed. Results There was no significant difference in ALT between the two groups. However, the increment of alkaline phosphatase, total bilirubin, and γ-GT transferase in adenosyl methionine group was less than that in control group, and bilirubin, alkaline phosphatase Indicators control effect is obvious. Conclusions Adenosine methionine is effective in protecting liver function during the perioperative period of TACE, especially for patients with elevated bilirubin.