Stevens-Johnson 氏综合征是一复杂的症状群,以皮肤、粘膜和眼部的三联损害为其特征。其前驱症状最常见的是急性咽炎或上呼吸道感染。紧接着出现皮肤的多形性损害,口腔和唇粘膜出现疱疹,眼部呈急性炎症表现。重症患者气管、支气管粘膜亦受侵犯。早在1866年 Von Hebra 最先以渗出性多形性红斑命名描述了此综合征,其特征是起病时发烧、咳嗽及全身不适或衰竭,皮肤和粘膜的多形性损害,偶尔伴有非典型的局灶性肺炎。至1922 Stevens-Johnson’s syndrome is a complex group of symptoms characterized by triple damage of the skin, mucous membranes and the eye. The most common prodromal symptoms are acute pharyngitis or upper respiratory tract infection. Followed by pleomorphic damage to the skin, oral and oral mucosal herpes appear, the eyes showed acute inflammation. Severe tracheal, bronchial mucosa are also violated. As early as 1866, Von Hebra first described the syndrome as exudative erythema multiforme characterized by fever, cough and general malaise or failure at onset, pleomorphic damage of the skin and mucous membranes, occasionally with Atypical focal pneumonia. To 1922